1256 Immunoprevention of chemical nevogenesis through early recognition of oncogene mutations

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Immunoprevention of chemical carcinogenesis through early recognition of oncogene mutations.

Prevention of tumors induced by environmental carcinogens has not been achieved. Skin tumors produced by polyaromatic hydrocarbons, such as 7,12-dimethylbenz(a)anthracene (DMBA), often harbor an H-ras point mutation, suggesting that it is a poor target for early immunosurveillance. The application of pyrosequencing and allele-specific PCR techniques established that mutations in the genome and ...

متن کامل

Improvement of Chemical Named Entity Recognition through Sentence-based Random Under-sampling and Classifier Combination

Chemical Named Entity Recognition (NER) is the basic step for consequent information extraction tasks such as named entity resolution, drug-drug interaction discovery, extraction of the names of the molecules and their properties. Improvement in the performance of such systems may affects the quality of the subsequent tasks. Chemical text from which data for named entity recognition is extracte...

متن کامل

THE MUTATIONS OF RET PROTO-ONCOGENE IN MEDULLARY THYROID CARCINOMAS IN IRAN

MeduIIary thyroid carcinoma (MTC) occurs both sporadically and in the autosomal dominantly inherited multiple endocrine neoplasia (MEN) type 2 syndromes. The distinction between true sporadic MTC and a new mutation familial case is important for future clinical management of both the patient and family. The susceptibility gene for hereditary MTC is the RET proto-oncogene. DNA analysis for g...

متن کامل

RET proto-oncogene mutations in the diagnosis of medullary thyroid cancer: a review article

Medullary thyroid cancer accounts for 5-10% of thyroid carcinomas. RET proto-oncogene mutations occur in all of the hereditary MTCs and about 66% of the sporadic MTCs. So, the detection of the RET mutations is necessary for rapid and proper diagnosis and treatment. This systematic review seeks to find a comprehensive list of RET gene mutations in the diagnosis of medullary thyroid cancer. The ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2018

ISSN: 0022-202X

DOI: 10.1016/j.jid.2018.03.1271